A Proven Treatment for Clostridium difficile colitis

Fecal Microbiota Transplant (FMT) involves taking stools from a healthy pre-screened donor and placed in the patient's colon or terminal ileum to recolonize healthy bacteria into their gastrointestinal system, usually by colonoscopy. The fecal matter is mixed with saline or other solution. FMT is use to treat Clostridium difficile colitis (C. diff) which is a bacterial infection in a patient's colon who have had an alteration in gastrointestinal flora usually due to antibiotics or hospitalization. C. diff affects a half million patients a year. C. diff can cause mild symptoms to severe episodes that can be life-threatening. Patients often experience chronic diarrhea, nausea, abdominal pain, fever, and weight loss. FMT has a 90% cure successful rate.

What to Expect

Preparation for the Procedure
  1. I'm dizzy or have a headache, what should I do?

    Dizziness and headache could be signs of low blood sugar. Drinking a regular carbonated beverage (not diet) or apple juice may alleviate these symptoms.

  2. What if I start to feel nauseated or start vomiting?

    Wait 15-30 minutes before continuing prep then start back slowly. You may also take a Benadryl to help control the nausea.

  3. What is the best "clear" liquid to take?

    Gatorade, which comes in many flavors, is an excellent choice as it contains electrolytes such as potassium. Avoid RED/BLUE liquids. We also recommend beef and chicken bouillon made from cubes (not broth). If you drink broth your procedure will be cancelled.

  4. Why avoid red/blue liquids?

    The color can persist in the colon and make an accurate diagnosis more difficult.

  5. Is there any way that I can make the prep taste better?

    You can try sucking on hard candy (except red or blue), but no candy four hours prior to your procedure. You can rinse your mouth with water or a mouthwash. Do not eat or drink anything other than approved liquids while you are drinking the solution.

  6. I already have diarrhea before taking the prep, do I still have to take the laxative?

    Yes, you must take the prep as directed by your doctor. Your colon is approximately 6 feet long. The entire colon must be emptied for your physician to see the colon clearly.

  7. I am taking the prep and already have loose, watery stool; do I still need the rest of the prep?

    Yes, you may have solid stool higher in the colon that needs to be eliminated.

  8. I see yellow color in the toilet bowl and a few flecks, what do I do?

    If your last bowel movements were clear enough that you were able to see the bottom of the toilet you should be fine. It is ok if you have some flecks of material. The yellow color is a result of the bile that normally colors the feces. This shouldn't interfere with the examination.

  9. My bottom is so sore. What can I do?

    To clean the area, avoid rubbing. Gently pat with a wet washcloth. Apply Vaseline, Preparation H, or Desitin liberally.

  10. Can I drink alcoholic beverages?

    We strongly suggest you do not drink any alcoholic beverages prior to your procedure since they can cause dehydration and some wines may thin your blood.

  11. Can I chew gum or suck candy?

    Yes, but nothing with soft centers or red color. No candy or gum is allowed 4 hours prior to your procedure.

  12. Can I have the colonoscopy done if I am having my menstrual period?

    Yes, the procedure can still be performed. We ask that you use a tampon if possible (not absolutely necessary).

  13. Do I need a prescription for the laxatives?

    It depends on the preparation instructions you were given. Suprep is a prescription medication; Miralax does not require a prescription.

  14. Why did my doctor want me to do a spilt prep (two doses taken X hours apart)?

    We have found that by splitting the prep, our patients have a better colonoscopy--a clearer colon results in an optimal examination so that the test does not have to be repeated due to an incomplete prep. If there is residual stool or murky liquid still in the colon, it will interfere with a thorough exam of the colon.

Day of Procedure Questions
  1. What should I wear?

    Loose, comfortable clothing is recommended. You can wear make up but we advise patients not to wear jewelry. If you wear contacts please bring your case and solution so that you can remove them prior to your procedure.

  2. Can I drive myself home after the procedure?

    No, since sedatives are used, another driver is needed. This driver MUST stay during the procedure or the procedure will not be performed. This is for your personal safety. You may bring more than one person with you, but only one person can be with you in recovery due to space limitations.

  3. What if I am still passing stool the morning of my test?

    Take a tap water enema until you run clear. If this does not work, call the office.

  4. One of the medications I was instructed to take the morning of my procedure is red. Can I take it?

    Medication for blood pressure, heart conditions, and seizure should be taken the morning of your exam regardless of the color. Light blue and light pink medications are also fine for you to take.

  5. Can I brush my teeth?

    Yes, please.

  6. Can I wear my dentures?

    Yes, you may wear your dentures to the Endoscopy suite. However, you may be asked to remove them prior to the procedure.

  7. Why do I have to be there an hour before my scheduled procedure time? What if I am running late?

    We ask patients to arrive early so that we can do a pre-procedure assessment and start the IV. Please call 864.232.7338 if you are running more than 15 minutes late, so that we can work together to adjust the schedule so that we can accommodate this delay.

After the Procedure Questions
  1. I am still dizzy and lightheaded after my procedure, why?

    You may have residual anesthesia in your system, additional rest is recommended. This will improve over the next few hours.

  2. My bottom is so sore. What can I do?

    To clean the area, avoid rubbing. Gently pat with a wet washcloth. Apply Vaseline, Preparation H, or Desitin liberally.

  3. May I go back to work after my procedure?

    No, please take it easy the rest of the day. Due to the sedatives, you may not think clearly for several hours. DO NOT DRIVE. You can return to work the day after your procedure, unless your physician specifically tells you otherwise.

  4. How do I get my results?

    Results are given by the doctor to you in the recovery room. You may or may not remember talking to the doctor so your results will also be in your discharge instructions. Pathology may take up to 2 weeks to get results. You will be given instructions on how to get your pathology results from the LabCall website or toll free telephone number anytime, day or night, or you can call the office during business hours. Your results will be available after the pathology lab has tested your biopsy/tissue sample and your physician has reviewed the results. It can take longer than expected if your physician is out of the office for an extended period.

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