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MASLD/MASH (Fatty Liver Disease)

  • MASLD (Metabolic dysfunction-associated steatotic liver disease) happens when too much fat builds up in the liver. This condition was previously known as fatty liver disease (NAFLD).

  • MASH (Metabolic dysfunction-associated steatohepatitis) is a more serious form of MASLD. In MASH, the fat in the liver causes inflammation and damages liver cells. This condition was previously called NASH.
    • If left untreated, MASH can lead to liver scarring, cirrhosis, or liver cancer. Treatment focuses on healthy lifestyle changes such as improving diet, losing weight, staying physically active, and managing conditions like diabetes and high cholesterol.

Treatments & Procedures

Blood Tests

MASLD and MASH are often “silent” conditions, meaning many people have no symptoms, especially in the early stages. Symptoms may not appear until liver damage has progressed. When symptoms do occur, they may include:

  • Fatigue
  • Mild pain or discomfort in the upper right abdomen
  • Unexplained weight loss
  • Swelling in the legs or abdomen (if cirrhosis develops)

In many cases, lifestyle changes can improve liver health.

Risk factors include obesity, diabetes, and high cholesterol.

Management focuses on lifestyle changes such as weight loss and diet improvement.

Gastroenterology Associates

Upstate South Carolina

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